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However, a 2025 review noted only 3 RCTs, calling for larger trials (Nguyen et al., 2025)

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This intricate assembly encompasses the NLRP3 protein, serving as a detector for inflammasome activation, and the apoptosis-associated speck-like protein containing the CARD complex (ASC)

(PubMed) Duffy B, McNulty H, Ward M, Pentieva K